Insulin is Not Associated to Colorectal Cancer Risk

An exploration coming from the Women’s Health Initiative has advised that colorectal cancer risk is involved with elevated fasting blood sugar levels, however, not with hyperinsulinaemia.

The research noted 81 cases of colorectal melanoma among a subgroup of 4,902 non-diabetic postmenopausal females that were followed for twelve years.

They had starvation serum insulin and blood sugar levels evaluated at baseline and insulin conflict was determined by the homeostasis model (HOMA-IR index). The majority had constant measurements throughout the study.

When compared with participants within the lowest tertile of baseline glucose had an improved risk of colorectal melanoma (hazard ratio 1.74). The result was more pronounced for colon cancer (HR 2.25).

However, serum insulin and HOMA-IR were not connected with melanoma risk. “These facts recommend that heightened serum sugar levels could be a threat for colorectal cancer in postmenopausal females,” the scientists said.