Thursday, 19 July 2012

Great Risk with High Ceramide Levels in Alzheimer's Disease


Higher levels of a certain fat within the bloodstream called ceramides may increase an individual's risk of establishing Alzheimer's disease, based on a study posted within the July 18, 2012, online concern about Neurology, the medical journal of the American Academy of Neurology.

Regarding the study, 99 females related to the ages of 70 and 79 and free of dementia in the Women's Health and Aging Study II had their own blood tested for quantities of serum ceramides, a fatty compound found through the entire body that is linked to inflammation and cell death. The individuals were absolutely placed into three groups: high, middle and low levels of ceramides. These were then followed for approximately nine years. As to the 99 individuals, 27 developed dementia and 18 patients were really diagnosed with probable Alzheimer's disease.

The research found that women who exactly had the highest quantities of the biomarker were 10 times very likely to develop Alzheimer's disease compared to ladies with the lowest stages. Those particular with middle stages of the biomarker were nearly eight times very likely to develop the disorder compared to those considering the lowest levels.

"These bits of information are very important as identifying a dependable biomarker for earlier Alzheimer's which needs little charge and inconvenience in an affected individual could help modify our center of attention from handling the disorder to actually preventing or delaying it," said Valory Pavlik, PhD, with the Alzheimer's Disease and Memory Disorders Center of Baylor College of Medicine in Houston as well as a membership owner the American Academy of Neurology, inside an accompanying editorial.

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