Tuesday, 19 June 2012

Phase 2 Trials in RCC Published by Cancer


Aeterna Zentaris Inc. introduced that statistics from two Phase 2 trials in renal cell carcinoma (RCC) regarding the Company's oral anticancer medication, perifosine, happen to published within the June 2012 issue of Cancer, a journal of the American Cancer Society.

The article is referred to as, "Two Phase 2 Trials of the Novel Akt Inhibitor Perifosine in Affected individuals along with Advanced Renal Cell Carcinoma after Development on Vascular Endothelial Growth Factor-Targeted Therapy.”

It outlines perifosine's exercise as monotherapy in affected individuals along with advanced RCC that was comparable to current second-line representatives. Both objective tumor solutions and prolonged disorder equilibrium were really seen, and perifosine was clearly tolerated with the 100mg daily dose utilized in this trial. Ultimately, the authors conclude the fact that compound can deserve further investigation within this indication in conjunction with available therapies.

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